Pathology Services - Specimen

King’s Liver Labs comprises of Liver Pathology Services and Academic Laboratories, processing about 120,000 diagnostic tests per year, and is an integral part of the Institute of Liver Studies at King’s College Hospital NHS Foundation Trust, London.

We provide. . .
  • 'Specialist' diagnostics and drug monitoring services.
  • Expert interpretative advice for the clinical management of liver patients at King’s and also for referring clinicians at centres across the United Kingdom and abroad.
Test (alphabetical order)Turnaround
Ciclosporin - LC-MS/MSwithin 24hrs.
Everolimus - LC-MS/MSwithin 24hrs.
Mycophenolic acid - LC-MS/MSwithin 24hrs.
Sirolimus - LC-MS/MSwithin 24hrs.
Tacrolimus - LC-MS/MSwithin 24hrs.
Ribavirin - LC-MS/MSwithin 4 weeks
HAV Ab (IgM)2 working days
HAV Ab (IgG)2 working days
HBsAg (Qualitative)2 working days
HBsAb2 working days
HBsAg Confirmatory5 working days
HBsAg Quantitative3 working days
HBeAg2 working days
HBeAb2 working days
HBcAb (IgM)2 working days
HBcAb2 working days
HBV DNA Quantitative4 working days
HBV Drug Resistance Mutation10 working days
HBV Genotype10 working days
HCV Ab2 working days
HCV Genotype5 working days
HCV RNA Quantitative3 working days
HDV Ab (Total)5 working days
HDV Ab (IgM)10 working days
HDV RNA Quantitative5 working days
HEV Ab (IgM)5 working days
HEV Ab (IgG)5 working days
HEV RNA15 working days
Liver Biopsy2 working days
HPB surgical specimens6 working days
Frozen SectionSame day
Digital Imagingtbc
Analysis of 28 genes by Next Generation Sequencing (NGS). (ATP8B1, ABCB11, ABCB4, AKR1D1, HSD3B7, CYP7B1, SLC27A5, AMACR, CYP7A1, CYP27A1, BAAT, TJP2, ABCC2, VPS33B, VIPAS39, JAG1, NOTCH2, excluding exons 1-4, DCDC2, BCS1L, CLDN1, TALDO1, NR1H4, SLC25A13, GNAS codons 201 and 227 only, NPC1, NPC2, UGT1A1, MYO5B40 working days
Analysis of the ATP7B gene using a combination of next generation and Sanger Sequencing.40 working days
Analysis of 8 genes by Next Generation Sequencing (NGS). (MYO5B, STX3, TTC37, SLC26A3, SKIV2, EPCAM, GUCY2C, SPINT2)40 working days
Sanger sequencing of variants identified in the genes tested by the laboratory.20 working days
Testing for three most common HFE variants -
p.Cys282Tyr (C282Y)
p.His63Asp (H63D)
p.Ser65Cys (S65C)
10 working days
Low definition HLA B27 genotyping 10 working days
Genotyping for the presence of the HLAB*57:01 allele10 working days
HLA DQ2 and DQ8 genotyping10 working days

Referral Forms & Information Leaflets

Form / documentDownload
HTS Specimen Referral
IDM Specimen Referral
Histology Specimen Referral
LMG Specimen Referral
Biobank - Information for Participants
Biobank - Information for Relatives
Patient and Service Complaints Procedure
User Handbook
UKAS - Schedule of Accreditation
Email us for more information.
Email: kch-tr.KCHLiverLabs@nhs.net`