test-icon HBV Drug Resistance Mutation

Purpose of Test: The HBV Drug Resistance Mutation Screen is used to detect anti-viral resistance mutations in patients undergoing treatment for HBV infection by the determination of nucleotide mutations that lead to amino acid changes responsible for resistance to HBV antiviral drugs.
Method: The HBV Drug Resistance Mutation Screen is an in vitro nucleic acid amplification and direct sequencing test.
Minimum Sample Requirements: 1.5mLs EDTA plasma preferred or serum.
Limit of Detection (LOD)/RANGE OF QUANTITATION: LOD 200 IU/mL. It is recommended that only samples with a VL >/= 200 IU/mL be referred for testing; samples with a lower VL may be sent but amplification cannot be guaranteed.
contact-icon Contacts
Hepatitis Testing Service: kch-tr.LiverHTS@nhs.net
Contact Lab for any queries.