test-icon HBsAb

Purpose of Test: The anti-HBs assay is used for quantitative determination of antibody to Hepatitis B surface antigen (anti-HBs) in human serum and plasma. Anti-HBs assays are used to monitor the success of Hepatitis B vaccination. Assays for anti-HBs are also used to monitor the convalescence and recovery of Hepatitis B infected individuals. The presence of anti-HBs after acute HBV infection and loss of Hepatitis B virus surface antigen (HBsAg) can be a useful indicator of disease resolution. Samples with anti-HBs concentration less than 10.0 mIU/mL are considered nonreactive. Samples with anti-HBs concentrations greater than or equal to 10.0 mIU/mL are considered reactive.
Method: Abbott ARCHITECT: automated chemiluminescent microparticle immunoassay (CMIA)
Minimum Sample Requirements: 300μL serum/EDTA plasma
Limit of Detection (LOD)/RANGE OF QUANTITATION: Range of quantitation 0.00 to 1000mIU/mL. Samples >1000mIU/mL can be manually diluted 1/100 though this is not routinely performed. Samples with anti-HBs concentrations greater than or equal to 10.0 mIU/mL are considered reactive.
contact-icon Contacts
Hepatitis Testing Service: kch-tr.LiverHTS@nhs.net
Contact Lab for any queries.