test-icon HBsAg Quantitation

Purpose of Test: The quantitative HBsAg assay is used for the quantitative determination of hepatitis B surface antigen (HBsAg) in human serum and plasma. Quantitation of HBV has a growing clinical utility in the monitoring of therapy in cases of chronic HBV with studies suggesting the use of HBsAg as a biomarker for the prognosis and response to therapy.
Method: Abbott ARCHITECT: automated chemiluminescent microparticle immunoassay (CMIA)
Minimum Sample Requirements: 300μL serum/EDTA plasma
Limit of Detection (LOD)/RANGE OF QUANTITATION: LOD 0.05 IU/mL. On-board auto-dilution 1/500 gives a range of 175 to 124,925 IU/mL. Samples with an initial result of <175 IU/mL are routinely re-tested neat to give an accurate HBsAg level. Samples with an initial result of >124,925 IU/mL can be be further diluted manually if required.
contact-icon Contacts
Hepatitis Testing Service: kch-tr.LiverHTS@nhs.net
Contact Lab for any queries.